New BFF Alert: Jen Aniston & Drew Barrymore

Drew & Jen at the Time for Heroes event in 1998 (BEIMAGES)

(wireimage.com)

Jennifer Aniston and Drew Barrymore enjoyed a girls' night out together over dinner at the celebrity favorite Tower Bar restaurant at L.A.'s chic Sunset Tower Hotel on Friday, Aug. 31 — Jen has been spotted there in the past with former flame Paul Sculfor.

The two friends were discussing their upcoming film project, He's Just Not That Into You, the movie they're shooting this month with Scarlett Johansson, Justin Long, Bradley Cooper, Jennifer Connelly and possibly Ben Affleck. Drew is also starring and producing the film. This is Jen's first movie since her self-imposed hiatus after splitting with Break-Up co-star Vince Vaughn.

They sat at a corner table after arriving at 8:30 and left separately two hours later. Jen was wearing a white cap-sleeved top — she's never looked better. Drew wore a dress. They drank sparkling mineral water and a little white wine, and split side order of truffle fries.

"There was lots of laughing and animated discussion," an eyewitness tells OK!